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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASSF1
All Species:
26.67
Human Site:
S163
Identified Species:
65.19
UniProt:
Q9NS23
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NS23
NP_009113.3
344
39219
S163
M
S
L
N
K
D
G
S
Y
T
G
F
I
K
V
Chimpanzee
Pan troglodytes
XP_001168270
344
39200
S163
M
S
L
N
K
D
G
S
Y
T
G
F
I
K
V
Rhesus Macaque
Macaca mulatta
XP_001100583
340
38751
S159
M
S
L
N
K
D
G
S
Y
T
G
F
I
K
V
Dog
Lupus familis
XP_850255
340
38828
S159
M
S
L
N
K
D
G
S
Y
T
G
F
I
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99MK9
340
38771
S159
M
S
L
N
K
D
G
S
Y
T
G
F
I
K
V
Rat
Rattus norvegicus
O35141
413
46661
T230
M
K
L
S
E
D
G
T
Y
T
G
F
I
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509318
287
32765
R137
P
T
L
H
D
A
K
R
P
A
G
K
S
Q
A
Chicken
Gallus gallus
NP_001007852
256
29478
F119
H
S
N
N
E
T
A
F
Y
L
P
N
D
C
V
Frog
Xenopus laevis
NP_001090617
273
31370
R134
R
S
Q
P
V
K
R
R
T
S
F
Y
L
P
K
Zebra Danio
Brachydanio rerio
NP_001004550
363
41903
S181
M
V
L
N
R
D
G
S
Y
T
G
F
I
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.3
92.4
N.A.
89.8
41.4
N.A.
60.4
37.7
52.3
53.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
97.9
94.4
N.A.
93.3
54.9
N.A.
68.3
50.5
64.5
66.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
73.3
N.A.
13.3
26.6
6.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
33.3
33.3
26.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
0
0
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
10
70
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
10
70
0
0
0
% F
% Gly:
0
0
0
0
0
0
70
0
0
0
80
0
0
0
0
% G
% His:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
70
0
0
% I
% Lys:
0
10
0
0
50
10
10
0
0
0
0
10
0
70
10
% K
% Leu:
0
0
80
0
0
0
0
0
0
10
0
0
10
0
0
% L
% Met:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
70
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
10
0
0
10
0
0
0
0
10
0
10
0
0
10
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
10
0
0
0
10
0
10
20
0
0
0
0
0
0
0
% R
% Ser:
0
70
0
10
0
0
0
60
0
10
0
0
10
0
0
% S
% Thr:
0
10
0
0
0
10
0
10
10
70
0
0
0
0
0
% T
% Val:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
80
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
80
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _